Medical Assistant Salary in Missouri

Medical Assistants in Missouri earn an average of $38,436 per year across 2 metro areas. This is +8.5% lower than the national average.

Average Salary

$38,436

per year

Hourly Rate

$18.48

per hour

vs National

-8.5%

$42,000 national

Salary Range

$24,862

to $54,937

Cost of Living Adjusted Salary

Nominal Salary

$38,436

Cost of Living Index

90

100 = national average

Adjusted Salary

$42,707

purchasing power equivalent

After adjusting for Missouri's cost of living (below average), a Medical Assistant's salary of $38,436 has the purchasing power of $42,707 in an average-cost area.

Medical Assistant Salary by City in Missouri

CityMedian SalaryHourly RateEntry Level (P10)Senior (P90)Employment
St. Louis, MO$38,837$18.67/hr$24,434$55,755688
Kansas City, MO$38,035$18.29/hr$25,290$54,119678

Source: Bureau of Labor Statistics OEWS Survey, 2026. Sorted by median salary (highest first).

Missouri vs National Average

Medical Assistant Salary Comparison

Missouri Average$38,436
National Average$42,000
Difference-$3,564 (-8.5%)

Employment in Missouri

There are approximately 1,366 Medical Assistants employed across 2 metro areas in Missouri.

Key Industries: Manufacturing, Healthcare, Agriculture

State Income Tax: 0% - 4.95%

Medical Assistant Salary Range in Missouri

Entry Level (10th Percentile)

$24,862

Starting salary for new Medical Assistants

Median (50th Percentile)

$38,436

Mid-career Medical Assistant salary

Senior (90th Percentile)

$54,937

Top earners in the field

Frequently Asked Questions

What is the average Medical Assistant salary in Missouri?

The average Medical Assistant salary in Missouri is $38,436 per year ($18.48/hour) based on 2026 data across 2 metro areas. This is 8.5% below the national average of $42,000.

What is the highest paying city for Medical Assistants in Missouri?

St. Louis, MO is the highest paying city for Medical Assistants in Missouri, with a median salary of $38,837 per year. The lowest paying metro area is Kansas City, MO at $38,035.

What is the salary range for Medical Assistants in Missouri?

Medical Assistant salaries in Missouri range from $24,862 (entry-level, 10th percentile) to $54,937 (experienced, 90th percentile). The median salary is $38,436 per year.

About This Data

Salary data is sourced from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey. State-level averages are calculated from metro area data within Missouri. Figures represent 2026 estimates and may not reflect all employers or self-employed workers. Cost of living adjustments use regional indices to provide purchasing power context.