Physician Assistant Salary in Missouri
Physician Assistants in Missouri earn an average of $120,111 per year across 2 metro areas. This is +7.6% lower than the national average.
Average Salary
$120,111
per year
Hourly Rate
$57.75
per hour
vs National
-7.6%
$130,020 national
Salary Range
$75,844
to $168,473
Cost of Living Adjusted Salary
Nominal Salary
$120,111
Cost of Living Index
90
100 = national average
Adjusted Salary
$133,457
purchasing power equivalent
After adjusting for Missouri's cost of living (below average), a Physician Assistant's salary of $120,111 has the purchasing power of $133,457 in an average-cost area.
Physician Assistant Salary by City in Missouri
| City | Median Salary | Hourly Rate | Entry Level (P10) | Senior (P90) | Employment |
|---|---|---|---|---|---|
| Kansas City, MO | $123,455 | $59.35/hr | $77,188 | $174,260 | 137 |
| St. Louis, MO | $116,766 | $56.14/hr | $74,500 | $162,686 | 153 |
Source: Bureau of Labor Statistics OEWS Survey, 2026. Sorted by median salary (highest first).
Missouri vs National Average
Physician Assistant Salary Comparison
Employment in Missouri
There are approximately 290 Physician Assistants employed across 2 metro areas in Missouri.
Key Industries: Manufacturing, Healthcare, Agriculture
State Income Tax: 0% - 4.95%
Physician Assistant Salary Range in Missouri
Entry Level (10th Percentile)
$75,844
Starting salary for new Physician Assistants
Median (50th Percentile)
$120,111
Mid-career Physician Assistant salary
Senior (90th Percentile)
$168,473
Top earners in the field
Related Occupations in Missouri
Nurse Practitioner
$115,974
avg in MO
-$4,137 vs Physician Assistant
Registered Nurse
$85,940
avg in MO
-$34,171 vs Physician Assistant
Dental Hygienist
$85,010
avg in MO
-$35,101 vs Physician Assistant
Licensed Practical Nurse
$55,161
avg in MO
-$64,950 vs Physician Assistant
Nursing Assistant
$35,373
avg in MO
-$84,738 vs Physician Assistant
Physician Assistant Salary in Neighboring States
Compare Physician Assistant salaries in Missouri with nearby states to find the best opportunities.
More Physician Assistant Data
Frequently Asked Questions
What is the average Physician Assistant salary in Missouri?
The average Physician Assistant salary in Missouri is $120,111 per year ($57.75/hour) based on 2026 data across 2 metro areas. This is 7.6% below the national average of $130,020.
What is the highest paying city for Physician Assistants in Missouri?
Kansas City, MO is the highest paying city for Physician Assistants in Missouri, with a median salary of $123,455 per year. The lowest paying metro area is St. Louis, MO at $116,766.
What is the salary range for Physician Assistants in Missouri?
Physician Assistant salaries in Missouri range from $75,844 (entry-level, 10th percentile) to $168,473 (experienced, 90th percentile). The median salary is $120,111 per year.
About This Data
Salary data is sourced from the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey. State-level averages are calculated from metro area data within Missouri. Figures represent 2026 estimates and may not reflect all employers or self-employed workers. Cost of living adjustments use regional indices to provide purchasing power context.